Dimethylamine → HCID 22759904, compound

HRID 1703759Notes

Reaction equation

HRID 1703759 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:11][CH2:10][CH2:9][N:8]([C:12](=[O:15])[CH2:13]Cl)[CH:7]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[C:6]=2[CH:22]=1.[CH3:23][NH:24][CH3:25]>C(Cl)Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:11][CH2:10][CH2:9][N:8]([C:12](=[O:15])[CH2:13][N:24]([CH3:25])[CH3:23])[CH:7]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[C:6]=2[CH:22]=1

Participants

4

Reactant 2

HCID 674DimethylamineHCID 22759901HCID 22759901, compound

Product 1

HCID 22759904HCID 22759904, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 4.78 g (14.2 millimoles) of the 7-chloro-4-(2-chloroacetyl)-5-phenyl-2,3,4,5-tetrahydro-1,4-benzoxazepine produced in step (a) in 150 ml of CH2Cl2 was saturated with dimethylamine gas at 0°. The flask was stoppered and the solution was stored at -15° for 16 hours.

Sources & evidence

ORD record
ord-72a23fc8f2c343c2a9b853c4cfa70c19
Source dataset
uspto-grants-1978_11
Patent number
US04125538

Reaction notes

Loading…