Hydrochloric Acid → HCID 86736151, compound

Participants

Reaction Conditions

Reaction Steps

2-[4-(p-Aminobenzyl)-1-piperazinyl]-8-ethyl-5,8-dihydro-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid (3.0 g) was dissolved in 300 ml of ethanol by heating at 80° C. To the hot solution was added 0.5 ml of concentrated hydrochloric acid and the mixture was allowed to stand in a refrigerator. The resulting precipitate was collected by filtration and recrystallized twice from ethanol containing a small amount of concentrated hydrochloric acid to give the product (2.2 g), m.p. above 300° C.

Provenance & Evidence