2-Mercaptoethanol → HCID 22760779, compound

HRID 1703803Notes

Reaction equation

[C:1]1(=[O:7])[O:6][C:4](=[O:5])[CH:3]=[CH:2]1.[OH:8][CH2:9][CH2:10][SH:11].N1CCCCC1.C(NC(C)C)(C)C>>[O:5]=[C:4]1[CH:3]([CH2:2][C:1]([OH:6])=[O:7])[S:11][CH2:10][CH2:9][O:8]1

Participants

Reactant 4

HCID 15672-Mercaptoethanol

HCID 7912Diisopropylamine

HCID 7923Maleic Anhydride

HCID 8082Piperidine

Product 1

HCID 22760779HCID 22760779, compound

Procedure

Analogously to Example 1, by reaction of maleic acid anhydride with 2-hydroxyethanethiol in the presence of piperidine (instead of diisopropylamine) and the usual working up, 2-oxo-1,4-oxathiane-3-acetic acid, m.p. = 96°-98° is obtained.

Sources & evidence

ORD record: ord-a78ccb32961c4859a2262c98c494aab6
Source dataset: uspto-grants-1978_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04125622

Reaction notes

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