Diisopropylamine → HCID 22760815, compound

HRID 1703804Notes

Reaction equation

HRID 1703804 reaction equation
[C:1]1(=[O:7])[O:6][C:4](=[O:5])[CH:3]=[CH:2]1.[OH:8][CH:9]([CH2:12][O:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=1)[CH2:10][SH:11].C(NC(C)C)(C)C>>[Cl:20][C:16]1[CH:15]=[C:14]([CH:19]=[CH:18][CH:17]=1)[O:13][CH2:12][CH:9]1[O:8][C:4](=[O:5])[CH:3]([CH2:2][C:1]([OH:6])=[O:7])[S:11][CH2:10]1

Participants

4

Reactant 3

HCID 7912DiisopropylamineHCID 7923Maleic AnhydrideHCID 128222641-(3-Chlorophenoxy)-3-sulfanylpropan-2-ol

Product 1

HCID 22760815HCID 22760815, compound

Procedure

Analogously to Example 1, from maleic acid anhydride and 2-hydroxy-3-m-chlorophenoxypropane-1-thiol in the presence of diisopropylamine and the usual working up of the reaction mixture, 6-m-chlorophenoxymethyl-2-oxo-1,4-oxathiane-3-acetic acid is obtained. It is separated into two isomers using chromatographic purification:

Sources & evidence

ORD record
ord-f7f8274833e141c2aca26861a7516e55
Source dataset
uspto-grants-1978_11
Patent number
US04125622

Reaction notes

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