Diazomethane → 6-Pentyl-6-methyl-2-oxo-1,4-oxathiane-3-acetic acid methyl ester

HRID 1703806Notes

Reaction equation

HRID 1703806 reaction equation
[CH2:1]([C:6]1([CH3:17])[O:11][C:10](=[O:12])[CH:9]([CH2:13][C:14]([OH:16])=[O:15])[S:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5].[N+](=[CH2:20])=[N-]>C(OCC)C>[CH3:20][O:15][C:14](=[O:16])[CH2:13][CH:9]1[S:8][CH2:7][C:6]([CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])([CH3:17])[O:11][C:10]1=[O:12]

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 227607726-Pentyl-6-methyl-2-oxo-1,4-oxathiane-3-acetic acid

Product 1

HCID 540715616-Pentyl-6-methyl-2-oxo-1,4-oxathiane-3-acetic acid methyl ester

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To 4.7 g of 6-pentyl-6-methyl-2-oxo-1,4-oxathiane-3-acetic acid, dissolved in 50 ml of diethyl ether, there is added dropwise, with stirring and ice cooling, ethereal diazomethane solution, until a pale yellow color just remained. After the usual working up, 6-pentyl-6-methyl-2-oxo-1,4-oxathiane-3-acetic acid methyl ester is obtained:

Workup

  1. additionthere is added dropwise

Sources & evidence

ORD record
ord-cc3291d3d0b0448a9faa656b28deb243
Source dataset
uspto-grants-1978_11
Patent number
US04125622

Reaction notes

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