N,N'-Dimethylthiourea → HCID 22760533, compound

HRID 1703910Notes

Reaction equation

HRID 1703910 reaction equation
[Cl:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:23])(=[O:22])[NH:13][CH:14]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)[CH:6]=1)=[O:4].[CH3:24][NH:25][C:26]([NH:28][CH3:29])=[S:27]>C(OCC)(=O)C>[ClH:1].[Cl:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]2([OH:4])[CH2:2][S:27][C:26](=[N:25][CH3:24])[N:28]2[CH3:29])=[CH:6][C:7]=1[S:12](=[O:23])(=[O:22])[NH:13][CH:14]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

4

Reactant 2

HCID 2723631N,N'-DimethylthioureaHCID 22760520HCID 22760520, compound

Product 1

HCID 22760533HCID 22760533, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

5.2 g of 2,4'-dichloro-3'-cyclooctylsulfamoylacetophenone and 1.8 g of 1,3-dimethylthiourea were reacted as prescribed in Example 23. To the reaction mixture were added 30 ml of ethyl acetate and the end product was filtered off. Colorless crystals, melting point: 192° C. (decomposition).

Workup

  1. filtrationthe end product was filtered off

Sources & evidence

ORD record
ord-9950fcc84f91416baa7ca62711163165
Source dataset
uspto-grants-1978_11
Patent number
US04125614

Reaction notes

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