HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Piromidic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 8-ethyl-5,8-dihydro-5-oxo-2-(pyrrolidinyl)pyrido(2,3-d)pyrimidine-6-carboxylate | HCID 118556 | — |
| Reactant | HCID 13052389 | HCID 13052389 | — |
| Solvent | Water | HCID 962 | — |
| Product | Piromidic Acid | HCID 4855 | — |
Reaction Steps
Saponification of this ester (5.5 g) under reflux in an alkaline solution (NaOH: 0.8 g / water: 40 cm3) gives, after acidification, the corresponding acid (pyromidic acid, melting point 322° C), which is identical to the product described in the literature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04125720 |
| Source dataset | uspto-grants-1978_11 |
| ORD ID | ord-c5adcf6e4a9941d98a5a6d24bc00ca79 |
| Source note | uspto-grants-1978_11 |