HCID 22760937, compound → HCID 22760943, compound

HRID 1703974Notes

Reaction equation

HRID 1703974 reaction equation
[O:1]=[C:2]1[CH2:20][CH2:19][C:5]2[C:6]3[CH:18]=[CH:17][CH:16]=[CH:15][C:7]=3[O:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:4]=2[CH2:3]1>C(O)(=O)C.O=[Pt]=O>[OH:1][CH:2]1[CH2:20][CH2:19][CH:5]2[C:6]3[CH:18]=[CH:17][CH:16]=[CH:15][C:7]=3[O:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[CH:4]2[CH2:3]1

Participants

4

Reactant 1

HCID 22760937HCID 22760937, compound

Product 1

HCID 22760943HCID 22760943, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 176Acetic AcidSolvent

Procedure

1.0 g of 2-keto-1,2,3,4-tetrahydro-tribenzo(b,d,f)-oxepine is added to a suspension of 10 mg PtO2 (Adams catalyst) in 50 ml glacial acetic acid. The mixture is put in a hydrogenation apparatus under hydrogen atmosphere and shaken for 3 hours. After that time the theoretical quantity of hydrogen has been absorbed. The mixture is then filtered to remove the catalyst, whereupon the filtrate is evaporated in vacuo, yielding a light yellow oil.

Workup

  1. customAfter that time the theoretical quantity of hydrogen has been absorbed
  2. filtrationThe mixture is then filtered
  3. customto remove the catalyst
  4. customwhereupon the filtrate is evaporated in vacuo
  5. customyielding a light yellow oil

Sources & evidence

ORD record
ord-5226e5a78b1a48a7814fabaa67e4d1b3
Source dataset
uspto-grants-1978_11
Patent number
US04125718

Reaction notes

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