Benzene → HCID 54335978, compound

HRID 1703976Notes

Reaction equation

HRID 1703976 reaction equation
O=[C:2]1[CH2:20][CH2:19][C:5]2[C:6]3[CH:18]=[CH:17][CH:16]=[CH:15][C:7]=3[O:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:4]=2[CH2:3]1.C1C=CC=CC=1.[O-]CC.[Na+].[C:31](#[N:33])[CH3:32]>>[C:31]([CH:32]=[C:2]1[CH2:20][CH2:19][C:5]2[C:6]3[CH:18]=[CH:17][CH:16]=[CH:15][C:7]=3[O:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:4]=2[CH2:3]1)#[N:33]

Participants

5

Reactant 4

HCID 241BenzeneHCID 6342AcetonitrileHCID 2723922Sodium ethoxideHCID 22760937HCID 22760937, compound

Product 1

HCID 54335978HCID 54335978, compound

Procedure

1 g of 2-keto-1,2,3,4-tetrahydro-tribenzo(b,d,f)-oxepine is mixed with 1 ml of benzene, 15 ml of acetonitrile and 0.5 g of molecular sieve (4 A). 50 mg of sodium-ethoxide are added and the mixture is heated for 3 hours (90°-100° C.). After cooling the mixture the molecular sieve is filtered off and the filtrate evaporated.

Workup

  1. temperaturethe mixture is heated for 3 hours (90°-100° C.)
  2. temperatureAfter cooling the mixture the molecular sieve
  3. filtrationis filtered off
  4. customthe filtrate evaporated

Sources & evidence

ORD record
ord-e09e56bd3b5545a6804e469476d03e42
Source dataset
uspto-grants-1978_11
Patent number
US04125718

Reaction notes

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