Potassium Hydroxide → HCID 22761125, compound

HRID 1704131Notes

Reaction equation

[Cl:1][C:2]1[CH:31]=[CH:30][C:5]([O:6][CH:7]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH:20]([O:22][C:23]3[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][CH:24]=3)[CH3:21])=[CH:14][CH:13]=2)[C:8]([O:10]C)=[O:9])=[CH:4][CH:3]=1.[OH-].[K+]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:6][CH:7]([C:12]2[CH:13]=[CH:14][C:15]([O:18][CH2:19][CH:20]([O:22][C:23]3[CH:24]=[CH:25][C:26]([Cl:29])=[CH:27][CH:28]=3)[CH3:21])=[CH:16][CH:17]=2)[C:8]([OH:10])=[O:9])=[CH:30][CH:31]=1

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 54300003HCID 54300003, compound

Product 1

HCID 22761125HCID 22761125, compoundYield 98.3%

Procedure

As described in Example 73, 6.2 g of methyl (p-chlorophenoxy){p-[2-(p-chlorophenoxy)propoxy]phenyl}acetate is hydrolyzed with 4 g of potassium hydroxide to give 5.91 g of gum. Crystallization from hexane-ether gives 4.73 g of off-white crystals. Recrystallization from chloroform-hexane gives white crystals, mp 146°-148° C.

Sources & evidence

ORD record: ord-c457231252fe4ab89587ebc60fc90145
Source dataset: uspto-grants-1978_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04125732

Reaction notes

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