3-(Trifluoromethyl)phenol → HCID 131711345, compound

HRID 1704135Notes

Reaction equation

HRID 1704135 reaction equation
Br[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH:15]([O:17][C:18]2[CH:23]=[CH:22][C:21]([C:24]([CH3:27])([CH3:26])[CH3:25])=[CH:20][CH:19]=2)[CH3:16])=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].[F:28][C:29]([F:38])([F:37])[C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([OH:36])[CH:31]=1>O1CCCC1>[CH3:6][O:5][C:3](=[O:4])[CH:2]([O:36][C:32]1[CH:31]=[C:30]([C:29]([F:28])([F:37])[F:38])[CH:35]=[CH:34][CH:33]=1)[C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH:15]([O:17][C:18]2[CH:23]=[CH:22][C:21]([C:24]([CH3:27])([CH3:26])[CH3:25])=[CH:20][CH:19]=2)[CH3:16])=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 73763-(Trifluoromethyl)phenolHCID 54324953HCID 54324953, compound

Product 1

HCID 131711345HCID 131711345, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

As described in Example 71, methyl bromo{p-[2-(p-tert-butylphenoxy)propoxy]phenyl}acetate (0.017 mole) is reacted with 2.75 g of α,α,α,-trifluoro-m-cresol in 75 ml of tetrahydrofuran at 80° C. for 18 hrs to give the product as a pale yellow gum.

Sources & evidence

ORD record
ord-d40928203d6d49d6b66dd206d94cd25c
Source dataset
uspto-grants-1978_11
Patent number
US04125732

Reaction notes

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