4-(Trifluoromethyl)phenol → HCID 86736165, compound

HRID 1704143Notes

Reaction equation

HRID 1704143 reaction equation
Br[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH:15]([O:17][C:18]2[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=2)[CH3:16])=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].[F:25][C:26]([F:35])([F:34])[C:27]1[CH:28]=[CH:29][C:30]([OH:33])=[CH:31][CH:32]=1>O1CCCC1>[F:25][C:26]([F:34])([F:35])[C:27]1[CH:32]=[CH:31][C:30]([O:33][CH:2]([C:7]2[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH:15]([O:17][C:18]3[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=3)[CH3:16])=[CH:9][CH:8]=2)[C:3]([O:5][CH3:6])=[O:4])=[CH:29][CH:28]=1

Participants

4

Reactant 2

HCID 678744-(Trifluoromethyl)phenolHCID 54386710HCID 54386710, compound

Product 1

HCID 86736165HCID 86736165, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

As described in Example 71, methyl bromo{p-[2-(p-fluorophenoxy)propoxy]phenyl}acetate (0.017 mole) is reacted with 2.75 g of α,α,α-trifluoro-p-cresol in 75 ml of tetrahydrofuran at 80° C. for 18 hrs to give the product as a pale amber gum.

Sources & evidence

ORD record
ord-3d17840529214f5d937e4eccfb8c2ddf
Source dataset
uspto-grants-1978_11
Patent number
US04125732

Reaction notes

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