HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 2-(p-Fluorophenoxy)ethanol O-methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 2-(4-Fluorophenoxy)ethanol | HCID 574361 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-(p-Fluorophenoxy)ethanol O-methanesulfonate | HCID 20378395 | — |
Reaction Steps
As for Example 56, 12.5 g of 2-(p-fluorophenoxy) ethanol is reacted with 7 ml of methanesulfonyl chloride in 100 ml of dichloromethane in the presence of 23 ml of triethylamine. The product (18 g) is obtained as a colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04125732 |
| Source dataset | uspto-grants-1978_11 |
| ORD ID | ord-d72bfea152a74cdfaa75511a6c81fb6e |
| Source note | uspto-grants-1978_11 |