Phosphorus sulfide (P2S5) → HCID 22758948, compound

Participants

Reaction Steps

A 500 ml flask equipped with heating mantle, condenser, and drying tube is charged with 27.25 g (0.125 mole) of phosphorus pentasulfide, 17.3 g (0.1 mole) of N-formylleucine methyl ester, and 250 ml of chloroform, and the contents are refluxed for 24 hours. The reaction mixture is thereupon cooled to room temperature, washed with 250 ml of 10% potassium hydroxide, and then washed with 250 ml of distilled water.

Provenance & Evidence