Hydrazinecarboxylic acid, ethyl ester → HCID 178473578, compound

HRID 1704191Notes

Reaction equation

HRID 1704191 reaction equation
[C:1]1([C:7]2[NH:8][CH:9]=[C:10]([CH:12]=O)[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:14]([O:18][CH2:19][CH3:20])(=[O:17])[NH:15][NH2:16]>C(O)C>[CH2:19]([O:18][C:14](=[O:17])[NH:15][N:16]=[CH:12][C:10]1[N:11]=[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[NH:8][CH:9]=1)[CH3:20]

Participants

4

Reactant 2

HCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 178519858HCID 178519858, compound

Product 1

HCID 178473578HCID 178473578, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Conditions

Temperature
0 °C

Procedure

2-Penyl-4-imidazolecarboxaldehyde (8.16 g) is dissolved in hot ethanol (200 ml). A hot solution of ethyl carbazate (5.52 g) in ethanol (50 ml) is added. A precipitate forms immediately and the mixture is heated and stirred for about 10 minutes. The mixture is then cooled to 0° C and the precipitate collected by filtration to yield the title product, m.p. 196°-200° C.

Workup

  1. temperatureA precipitate forms immediately and the mixture is heated
  2. filtrationthe precipitate collected by filtration

Sources & evidence

ORD record
ord-3f1daf010355402885cda1cd9330b407
Source dataset
uspto-grants-1978_11
Patent number
US04126444

Reaction notes

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