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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1704376Generated: October 31, 2026

3-(Dimethylamino)propyl chloride hydrochloride → Dimaprit hydrochloride

https://huagongshe.com/reaction/1704376

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Dimethylamino)propyl chloride hydrochlorideHCID 94308—
ReactantThioureaHCID 2723790—
SolventEthanolHCID 702—
ProductDimaprit hydrochlorideHCID 90045—

Reaction Steps

Equimolar quantities of thiourea and 3-(dimethylamino)-1-chloropropane hydrochloride and a little ethanol are heated together at 140° for 3 hours, and the cooled mixture is recrystallised from methanol/isopropanol to give the title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04126670
Source datasetuspto-grants-1978_11
ORD IDord-9062996cf30a4f2d8df7903bf697b00e
Source noteuspto-grants-1978_11