Hydrogen Bromide → HCID 22759363, compound

Participants

Reaction Steps

A mixture of 3-(diethylamino)propyl alcohol (65.5 g), thiourea (38.0 g) and aqueous hydrobromic acid (48%, 25 ml) was boiled under reflux for 17 hours, and evaporated to dryness. The residue was triturated with ethanol and recrystallised from ethanol/methanol to give the title product, m.p. 125°-127° which was further recrystallised from absolute ethanol to give a 10.0 g sample with m.p. 144°-145°.

Provenance & Evidence