Magnesium → HCID 178461155, compound

HRID 1704380Notes

Reaction equation

[Mg:1].[CH3:2][C@@H:3]1[C@@H:17]2[C:12](=[C:13]([OH:32])[C@:14]3([OH:31])[C:22](=[O:23])[C:21]([C:24]([NH2:26])=[O:25])=[C:20]([OH:27])[C@@H:19]([N:28]([CH3:30])[CH3:29])[C@@H:15]3[C@H:16]2[OH:18])[C:10](=[O:11])[C:9]2[C:8]([OH:33])=[CH:7][CH:6]=[CH:5][C:4]1=2>>[Mg:1].[CH3:2][C@@H:3]1[C@@H:17]2[C:12](=[C:13]([OH:32])[C@:14]3([OH:31])[C:22](=[O:23])[C:21]([C:24]([NH2:26])=[O:25])=[C:20]([OH:27])[C@@H:19]([N:28]([CH3:29])[CH3:30])[C@@H:15]3[C@H:16]2[OH:18])[C:10](=[O:11])[C:9]2[C:8]([OH:33])=[CH:7][CH:6]=[CH:5][C:4]1=2

Participants

Reactant 2

HCID 5462224Magnesium

HCID 178461152HCID 178461152, compound

Product 1

HCID 178461155HCID 178461155, compound

Procedure

Magnesium ions combine with doxycycline in solution to form magnesium-doxycycline chelates. Magnesium oxide is a convenient and preferred source of magnesium ions, but other magnesium compounds useful for the purpose of this invention include magnesium chloride, magnesium acetate and magnesium sulfate. The molar ratio of magnesium to doxycycline in these compositions is preferably about from 1.8 to 2.2.

Sources & evidence

ORD record: ord-3213ced261974d08a0bff12b113dc83f
Source dataset: uspto-grants-1978_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04126680

Reaction notes

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