4-Bromophenacyl bromide → HCID 70616765, compound

HRID 1704714Notes

Reaction equation

HRID 1704714 reaction equation
[Br:1][C:2]1[CH:11]=[CH:10][C:5]([C:6](=[O:9])[CH2:7]Br)=[CH:4][CH:3]=1.[CH3:12][N:13]1[CH2:18][NH:17][C:16](=[S:19])[NH:15][CH2:14]1>CC(C)=O>[Br:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]2([OH:9])[N:17]3[CH2:18][N:13]([CH3:12])[CH2:14][N:15]=[C:16]3[S:19][CH2:7]2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 74544-Bromophenacyl bromideHCID 2525988Triazinthion

Product 1

HCID 70616765HCID 70616765, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

A solution of 6.95 grams (0.025 moles) of p-bromophenacylbromide in 60 milliliters of acetone was mixed with a solution of 3.27 grams (0.025 moles) of 3,4,5,6-tetrahydro-5-methyl-s-triazin 2(1H) thione in 450 milliliters of acetone. 6-p-Bromophenyl-6-hydroxy-3,4,6,7-tetrahydro-2H-thiazolo[3,2-a-]-s-triazine hydrobromide crystallized out as a colourless solid, m.p. 138°-140° C. (decomposition). The yield was 7.5 grams (75%).

Workup

  1. custom6-p-Bromophenyl-6-hydroxy-3,4,6,7-tetrahydro-2H-thiazolo[3,2-a-]-s-triazine hydrobromide crystallized out as a colourless solid, m.p. 138°-140° C. (decomposition)

Sources & evidence

ORD record
ord-14e6f7a7b7b44aa4897789eafbcf1beb
Source dataset
uspto-grants-1978_11
Patent number
US04127660

Reaction notes

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