Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Methyl chloroacetate | HCID 7295 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 22758706 | HCID 22758706 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 53860210 | HCID 53860210 | 88% |
Reaction Steps
A mixture of 3-hydroxy-8-methoxychromone (1.92 g, 0.01 mole), methyl chloracetate (1.08 g, 0.01 mole) and potassium carbonate (1.0 g, 0.01 mole) in dimethylformamide (20 ml) is stirred at 100° C. under nitrogen for 4 hrs. The reaction mixture is allowed to stand at room temperature overnight, poured into water, filtered, washed with water and sucked dry. Recrystallization from ethanol gives white crystals (2.3 g, 88%), mp 137°-138° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04127669 |
|---|
| Source dataset | uspto-grants-1978_11 |
|---|
| ORD ID | ord-b36bbd7fffcd4982950e2d122d22d5e8 |
|---|
| Source note | uspto-grants-1978_11 |
|---|
