Water → HCID 53860210, compound

HRID 1704744Notes

Reaction equation

HRID 1704744 reaction equation
[OH:1][C:2]1[C:11](=[O:12])[C:10]2[C:5](=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][CH:9]=2)[O:4][CH:3]=1.Cl[CH2:16][C:17]([O:19][CH3:20])=[O:18].C(=O)([O-])[O-].[K+].[K+].O>CN(C)C=O>[CH3:20][O:19][C:17](=[O:18])[CH2:16][O:1][C:2]1[C:11](=[O:12])[C:10]2[CH:9]=[CH:8][CH:7]=[C:6]([O:13][CH3:14])[C:5]=2[O:4][CH:3]=1

Participants

6

Reactant 4

HCID 962WaterHCID 7295Methyl chloroacetateHCID 11430Potassium CarbonateHCID 22758706HCID 22758706, compound

Product 1

HCID 53860210HCID 53860210, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of 3-hydroxy-8-methoxychromone (1.92 g, 0.01 mole), methyl chloracetate (1.08 g, 0.01 mole) and potassium carbonate (1.0 g, 0.01 mole) in dimethylformamide (20 ml) is stirred at 100° C. under nitrogen for 4 hrs. The reaction mixture is allowed to stand at room temperature overnight, poured into water, filtered, washed with water and sucked dry. Recrystallization from ethanol gives white crystals (2.3 g, 88%), mp 137°-138° C.

Workup

  1. waitto stand at room temperature overnight
  2. filtrationfiltered
  3. washwashed with water
  4. customsucked dry
  5. customRecrystallization from ethanol

Sources & evidence

ORD record
ord-b36bbd7fffcd4982950e2d122d22d5e8
Source dataset
uspto-grants-1978_11
Patent number
US04127669

Reaction notes

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