HCID 53860210, compound → HCID 22758703, compound

HRID 1704745Notes

Reaction equation

HRID 1704745 reaction equation
[CH3:1][O:2][C:3]1[C:12]2[O:11][CH:10]=[C:9]([O:13][CH2:14][C:15]([O:17]C)=[O:16])[C:8](=[O:19])[C:7]=2[CH:6]=[CH:5][CH:4]=1>Cl>[CH3:1][O:2][C:3]1[C:12]2[O:11][CH:10]=[C:9]([O:13][CH2:14][C:15]([OH:17])=[O:16])[C:8](=[O:19])[C:7]=2[CH:6]=[CH:5][CH:4]=1

Participants

3

Reactant 1

HCID 53860210HCID 53860210, compound

Product 1

HCID 22758703HCID 22758703, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Conditions

Temperature
100 °C

Procedure

A suspension of methyl [(8-methoxy-4-oxo-4H-1-benzopyran-3-yl)oxy]acetate (200 mg) in 6N hydrochloric acid (20 ml) is stirred at 100° C. for 3 hrs. under nitrogen. The reaction is cooled and the product filtered off and sucked dry. Recrystallization from methanol gives white crystals (180 mg. 86%), mp 215°-217° C.

Workup

  1. temperatureThe reaction is cooled
  2. filtrationthe product filtered off
  3. customsucked dry
  4. customRecrystallization from methanol
  5. customgives white crystals (180 mg. 86%), mp 215°-217° C.

Sources & evidence

ORD record
ord-1eca56f854fc49ffaaabf3ce3312b38c
Source dataset
uspto-grants-1978_11
Patent number
US04127669

Reaction notes

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