Hydrogen Peroxide → HCID 178502523, compound

HRID 1704750Notes

Reaction equation

HRID 1704750 reaction equation
[CH:1]([NH:3][C:4]1[CH:9]=[C:8]([S:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:7]=[CH:6][C:5]=1[NH:17][C:18]([NH:24][C:25]([O:27][CH3:28])=[O:26])=[N:19][C:20]([O:22][CH3:23])=[O:21])=[O:2].[OH:29]O>C(OC(=O)C)(=O)C>[CH:1]([NH:3][C:4]1[CH:9]=[C:8]([S:10]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)=[O:29])[CH:7]=[CH:6][C:5]=1[NH:17][C:18]([NH:24][C:25]([O:27][CH3:28])=[O:26])=[N:19][C:20]([O:22][CH3:23])=[O:21])=[O:2]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 178502521HCID 178502521, compound

Product 1

HCID 178502523HCID 178502523, compound

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

10.9 g of N-(2-formamido-4-phenylthiophenyl)-N',N"-bis(carbomethoxy)guanidine (Example 1) are dissolved in 200 ml of acetic anhydride. 25.8 ml of hydrogen peroxide (30% strength) are added and the mixture is stirred for 4 hours at 20° and is then concentrated in vacuo, and the residue is recrystallized from ethyl acetate to yield N-(2-formamido-4-phenylsulfinylphenyl)-N',N"-bis(carbomethoxy)guanidine (7.37 g), m.p. 168° C. (dec.).

Workup

  1. concentrationis then concentrated in vacuo
  2. customthe residue is recrystallized from ethyl acetate

Sources & evidence

ORD record
ord-478a1abadaba4259a49c98cb2c8c033a
Source dataset
uspto-grants-1978_11
Patent number
US04127670

Reaction notes

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