Pyrazole → 8-ethyl-5-(1-pyrazolyl)-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidine

HRID 1704769Notes

Reaction equation

HRID 1704769 reaction equation
N1C=CC=N1.C[N:7]([CH3:12])[CH2:8][CH2:9][CH2:10][NH2:11].[C:13]([N:21]1[C:25]2[N:26]=[CH:27][C:28]3C(OC4C=CC=CC=4)=[N:30][C:31]4[N:32]([N:34]=[CH:35][N:36]=4)[C:33]=3[C:24]=2[CH:23]=[N:22]1)(=O)[C:14]1C=CC=CC=1>>[CH2:13]([N:21]1[C:25]2[N:26]=[CH:27][C:28]3[C:12]([N:7]4[CH:8]=[CH:9][CH:10]=[N:11]4)=[N:30][C:31]4[N:32]([N:34]=[CH:35][N:36]=4)[C:33]=3[C:24]=2[CH:23]=[N:22]1)[CH3:14]

Participants

4

Reactant 3

HCID 1048PyrazoleHCID 7993N,N-Dimethyl-1,3-propanediamineHCID 227585058-Benzoyl-5-phenyloxy-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine

Product 1

HCID 227584818-ethyl-5-(1-pyrazolyl)-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidine

Procedure

By substituting pyrazole for the 3-(dimethylamino)propylamine in the procedure of Example 1 (c), 8-ethyl-5-(1-pyrazolyl)-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidine is obtained.

Sources & evidence

ORD record
ord-b3b3f10451814af393f61833419df610
Source dataset
uspto-grants-1978_11
Patent number
US04127655

Reaction notes

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