反应详情

A stirred mixture of diethyl isoquinolylaminomethylenemalonate (32.0 g., 0.0986 mole) and diphenyl ether (125 ml.) under nitrogen was heated at a temperature of 235° for 15 minutes. The solid, m.p. 183°-184°, obtained upon cooling and dilution with Skellysolve B was recrystallized from ethanol to give salmon crystals (22 g., 83% yield), m.p. 189°-191°. An analytical sample, recrystallized from ethanol, had m.p. 190°-192°.

1. temperaturewas heated at a temperature of 235° for 15 minutes
2. customThe solid, m.p. 183°-184°, obtained
3. temperatureupon cooling
4. customdilution with Skellysolve B was recrystallized from ethanol
5. customto give salmon crystals (22 g., 83% yield), m.p. 189°-191°
6. customAn analytical sample, recrystallized from ethanol