Hydrochloric Acid → Hydrochloric Acid

HRID 170488Notes

Reaction equation

HRID 170488 reaction equation
[Cl:32][CH2:33][Cl:34].[ClH:31].[O:25]1[CH2:26][CH2:27][O:28][CH2:29][CH2:30]1.[c:1]1(-[c:7]2[n:8][c:9]([CH:12]3[CH2:13][CH2:14][N:15]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:16][CH2:17]3)[s:10][cH:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[ClH:31].[c:1]1(-[c:7]2[n:8][c:9]([CH:12]3[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]3)[s:10][cH:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 67109295Tert-butyl 4-(4-phenyl-1,3-thiazol-2-yl)piperidine-1-carboxylate

Product 2

HCID 313Hydrochloric AcidHCID 242618344-Phenyl-2-(piperidin-4-yl)thiazole

Sources & evidence

ORD record
ord-d536c2f393b74f368fbe8364471b7c18
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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