Chlorine → HCID 70592300, compound

HRID 1706122Notes

Reaction equation

HRID 1706122 reaction equation
[O:1]=[C:2]([CH2:8][N:9]1[CH:12](SC)[CH2:11][C:10]1=[O:15])[CH2:3][C:4]([O:6][CH3:7])=[O:5].[Cl:16]Cl>C(Cl)(Cl)(Cl)Cl>[C:4](/[C:3](/[Cl:16])=[C:2]1\[CH2:8][N:9]2[CH:12]([O:1]\1)[CH2:11][C:10]2=[O:15])([O:6][CH3:7])=[O:5]

Participants

4

Reactant 2

HCID 24526ChlorineHCID 20336588HCID 20336588, compound

Product 1

HCID 70592300HCID 70592300, compoundYield 119.3%

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent2×

Procedure

Methyl 3-oxo-4-(2-oxo-4-methylthioazetidin-1-yl)butyrate (120 mg, 0.52 mmole) was dissolved in dry carbon tetrachloride (15 ml) and the solution was stirred and ice-cooled while chlorine (75 mg, 1.05 mmole) in carbon tetrachloride (1.4 ml) was added in one portion. The cooling bath was removed and stirring was continued for 10 minutes. The solvent was then evaporated under reduced pressure to yield a pale yellow gum (135 mg).

Workup

  1. additionwas added in one portion
  2. customThe cooling bath was removed
  3. stirringstirring
  4. customThe solvent was then evaporated under reduced pressure

Sources & evidence

ORD record
ord-34b633b0c49f4c8ba41bece6c03d4671
Source dataset
uspto-grants-1980_06
Patent number
US04206120

Reaction notes

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