Chlorine → HCID 70592300, compound

Participants

Reaction Steps

Methyl 3-oxo-4-(2-oxo-4-methylthioazetidin-1-yl)butyrate (120 mg, 0.52 mmole) was dissolved in dry carbon tetrachloride (15 ml) and the solution was stirred and ice-cooled while chlorine (75 mg, 1.05 mmole) in carbon tetrachloride (1.4 ml) was added in one portion. The cooling bath was removed and stirring was continued for 10 minutes. The solvent was then evaporated under reduced pressure to yield a pale yellow gum (135 mg).

Provenance & Evidence