HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Oxo-2,2,5,7-tetramethyl-7-(1-o-nitrobenzylcarbonyldioxymethyl)-3-oxa-1-azabicyclo[4.2.0]octane → 3-Methyl-1-(2-tetrahydropyranyl)-3-(o-nitrobenzylcarbonyldioxymethyl)-4-[1-methyl-2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Oxo-2,2,5,7-tetramethyl-7-(1-o-nitrobenzylcarbonyldioxymethyl)-3-oxa-1-azabicyclo[4.2.0]octane | HCID 20337377 | — |
| Reactant | 8-Oxo-2,2,5,7-tetramethyl-7-(hydroxymethyl)-3-oxa-1-azabicyclo[4.2.0]octane | HCID 20449448 | — |
| Reactant | 3-Methyl-1-(2-tetrahydropyranyl)-3-(hydroxymethyl)-4-[1-methyl-2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinone | HCID 23333025 | — |
| Product | 3-Methyl-1-(2-tetrahydropyranyl)-3-(o-nitrobenzylcarbonyldioxymethyl)-4-[1-methyl-2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinone | HCID 20337376 | — |
Reaction Steps
Following the procedure described for the preparation of 8-oxo-2,2,5,7-tetramethyl-7-(1-o-nitrobenzylcarbonyldioxymethyl)-3-oxa-1-azabicyclo[4.2.0]octane from 8-oxo-2,2,5,7-tetramethyl-7-(1-hydroxymethyl)-3-oxa-1-azabicyclo[4.2.0]octane and using 3-methyl-1-(2-tetrahydropyranyl)-3-(hydroxymethyl)-4-[1-methyl-2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinone there is obtained 3-methyl-1-(2-tetrahydropyranyl)-3-(o-nitrobenzylcarbonyldioxymethyl)-4-[1-methyl-2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04206219 |
| Source dataset | uspto-grants-1980_06 |
| ORD ID | ord-8dfa4ffa18334e2b89da226c6a8a2122 |
| Source note | uspto-grants-1980_06 |