Ethyl pyruvate → HCID 73677025, compound

HRID 1706158Notes

Reaction equation

HRID 1706158 reaction equation
Cl.[CH2:2]([NH:9][NH2:10])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[C:11]([O:16][CH2:17][CH3:18])(=[O:15])[C:12]([CH3:14])=O>C(O)C>[CH2:2]([NH:9][N:10]=[C:12]([CH3:14])[C:11]([O:16][CH2:17][CH3:18])=[O:15])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 12041Ethyl pyruvateHCID 12859630HCID 12859630, compound

Product 1

HCID 73677025HCID 73677025, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4.0 g. Heptylhydrazine hydrochloride are dissolved in 40 ml. ethanol and 2.3 g. ethyl pyruvate added thereto. The solution is left to stand for 20 minutes at ambient temperature, then mixed with 160 ml. water and the oil which separates out is extracted with diethyl ether. The ethereal solution is washed several times with a 2 N aqueous sodium carbonate solution and then with water, dried over anhydrous sodium sulphate and evaporated. The ethyl 2-(heptylhydrazono)-propionate obtained as residue does not crystallize. The yield is 3.7 g. (82.4% of theory).

Workup

  1. waitThe solution is left
  2. additionmixed with 160 ml
  3. extractionwater and the oil which separates out is extracted with diethyl ether
  4. washThe ethereal solution is washed several times with a 2 N aqueous sodium carbonate solution
  5. dry with materialwith water, dried over anhydrous sodium sulphate
  6. customevaporated

Sources & evidence

ORD record
ord-f8ab0126bd3649989bf836642af7c21c
Source dataset
uspto-grants-1980_06
Patent number
US04206231

Reaction notes

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