Ethylene Oxide → HCID 53643383, compound

Participants

Reaction Steps

38.6 g 4,4-dimethyl-decahydro-1,5-benzodiazepin-2-one is placed in a 250 ml flask with a slight molar excess of ethylene oxide (about 13.2 g) dissolved in ethyl alcohol. The reaction is run in an autoclave at 170°-180° C. A viscous brown paste is obtained which is dissolved in benzene. Upon recrystallization from benzene a white solid is obtained having a melting pt. 154°-156° C.

Provenance & Evidence