Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Mci-186 → Triethylammonium salt-methanolate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Mci-186 | HCID 4021 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Benzene, 1,4-dichloro-2-isocyanato- | HCID 79360 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | Triethylammonium salt-methanolate | HCID 19855321 | — |
| 생성물 | 1-Phenyl-3-methyl-4-(2,5-dichlorophenylcarbamoyl)-2-pyrazolin-5-one | HCID 20335428 | — |
반응 단계
The solution of 4.7 g of 1-phenyl-3-methyl-2-pyrazolin-5-one in 75 ml of benzene and 3.3 g of triethylamine is combined with the solution of 5.1 g of 2,5-dichlorophenylisocyanate in 25 ml of benzene. After warming the mixture briefly on the steam cone, the resulting solution is allowed to stand for 2 hours at room temperature. It is evaporated, the residue triturated with diethyl ether and recrystallized from methanol-diethyl ether to yield the triethylammonium salt-methanolate of the 1-phenyl-3-methyl-4-(2,5-dichlorophenylcarbamoyl)-2-pyrazolin-5-one, melting at 142°-147°, resolidifying and remelting at 154°-159°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04207317 |
| 출처 데이터셋 | uspto-grants-1980_06 |
| ORD ID | ord-49370d02af14492aa1a4cb74d165d926 |
| 출처 메모 | uspto-grants-1980_06 |