HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfate → 2-Benzoyl-3-nitro-6-methylmercapto-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | HCID 178519505 | HCID 178519505 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 2-Benzoyl-3-nitro-6-methylmercapto-pyridine | HCID 54068317 | — |
Reaction Steps
150 grams of 2-benzoyl-3-nitro-6-mercaptopyridine were dissolved in a solution of 45 grams of sodium hydroxide in 2.5 liters of water and hereto there was added dropwise at 35° C. with stirring 90 ml. of dimethyl sulfate. Then the composition was stirred for one hour at 40° C. After cooling the precipitated crystals were filtered off with suction and recrystallized from 1.8 liters of methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04207322 |
| Source dataset | uspto-grants-1980_06 |
| ORD ID | ord-8dd1fdca344f4d409a0a60a713056135 |
| Source note | uspto-grants-1980_06 |