Dimethylamine → HCID 20335754, compound

HRID 1706418Notes

Reaction equation

HRID 1706418 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:14]2[N:15]=[C:16](Cl)[CH:17]=[CH:18][C:13]=2[N:12]2[CH:20]=[N:21][N:22]=[C:11]2[CH2:10][N:9]=1.[CH3:23][NH:24][CH3:25].C(O)C>CO>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:14]2[N:15]=[C:16]([N:24]([CH3:25])[CH3:23])[CH:17]=[CH:18][C:13]=2[N:12]2[CH:20]=[N:21][N:22]=[C:11]2[CH2:10][N:9]=1

Participants

5

Reactant 3

HCID 674DimethylamineHCID 702EthanolHCID 68832Zapizolam

Product 1

HCID 20335754HCID 20335754, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

This compound was obtained in an analogous manner to that given in Example 10a from 15 grams of 6-(o-chloro-phenyl)-8-chloro-4H-s-triazolo-(4,3-a)-pyrido-(2,3-f)-(1,4)-diazepine and 55 grams of dimethylamine in 500 ml. of ethanol by heating for 5 hours at 120° C. M.P. 240°-242° C. (from methanol); Yield 8.5 grams.

Workup

  1. customThis compound was obtained in an analogous manner to

Sources & evidence

ORD record
ord-19f174103fb74780bc4ed039568de886
Source dataset
uspto-grants-1980_06
Patent number
US04207322

Reaction notes

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