Tetrahydrofuran → 4-(4-bromo-1-methyl-1H-pyrazol-5-yl)-5-chloro-2-thiophenecarboxylic acid

HRID 170648Notes

Reaction equation

HRID 170648 reaction equation
[Cl:1][c:2]1[c:3](-[c:10]2[cH:11][cH:12][n:13][n:14]2[CH3:15])[cH:4][c:5]([C:7](=[O:8])[OH:9])[s:6]1.[O:16]=[C:17]1[N:18]([Br:23])[C:19](=[O:20])[CH2:21][CH2:22]1.[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1>>[Cl:1][c:2]1[c:3](-[c:10]2[c:11]([Br:23])[cH:12][n:13][n:14]2[CH3:15])[cH:4][c:5]([C:7](=[O:8])[OH:9])[s:6]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 67184N-bromobutanimideHCID 578263895-chloro-4-(1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxylic acid

Product 1

HCID 578264444-(4-bromo-1-methyl-1H-pyrazol-5-yl)-5-chloro-2-thiophenecarboxylic acid

Sources & evidence

ORD record
ord-68df833f77ce4ebaa14c02215ab1ca45
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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