Sodium ethoxide → HCID 54493047, compound

HRID 1706689Notes

Reaction equation

HRID 1706689 reaction equation
[CH3:1][C:2]1[S:3][C:4]([CH2:12][CH2:13][CH2:14][C:15]([O:17]CC)=O)=[C:5](C(OCC)=O)[N:6]=1.[O-]CC.[Na+]>>[CH3:1][C:2]1[S:3][C:4]2[CH2:12][CH2:13][CH2:14][C:15](=[O:17])[C:5]=2[N:6]=1

Participants

3

Reactant 2

HCID 2723922Sodium ethoxideHCID 20334088HCID 20334088, compound

Product 1

HCID 54493047HCID 54493047, compoundYield 26%

Procedure

The compound is prepared from the product obtained in step (a), by cyclization with sodium ethoxide, followed by hydrolysis and decarboxylation of the crude ester. B.p.0.2 =130°-140° C. M.p.=86°-87° C. Overall yield: 26%.

Workup

  1. customB.p.0.2 =130°-140° C

Sources & evidence

ORD record
ord-a3c8a847ba1c43b2b1c37e57ca0f6cd0
Source dataset
uspto-grants-1980_06
Patent number
US04208420

Reaction notes

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