反应详情

温度

30 °C

86 g of ethyl 2,3-dibromopropionate was added, over a 15-minute period, to a stirred mixture of 41 g of 6A, 97 g of potassium carbonate and 300 ml of acetone. The temperature of the mixture rose to 60° C. The mixture was refluxed for 19 hours, cooled to 30° C. and filtered. The solvent was evaporated from the filtrate under reduced pressure. The residue was recrystallized from hexane to give 6, mp: 71°-72° C.

1. customrose to 60° C
2. temperatureThe mixture was refluxed for 19 hours
3. filtrationfiltered
4. customThe solvent was evaporated from the filtrate under reduced pressure
5. customThe residue was recrystallized from hexane
6. customto give 6, mp: 71°-72° C.