Diazomethane → HCID 86737062, compound

HRID 1706862Notes

Reaction equation

HRID 1706862 reaction equation
[CH2:1]1[CH2:30][O:29][C:20]2([O:25][CH2:26][CH2:27][O:28][C:3]2([CH:4]=[CH:5][C@@H:6]2[C@@H:10]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18])[CH2:9][CH2:8][CH2:7]2)[O:2]1)[CH2:21][CH2:22][CH2:23][CH3:24].[N+](=[CH2:33])=[N-]>>[CH3:33][O:18][C:17](=[O:19])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][C@@H:10]1[C@@H:6]([CH:5]=[CH:4][C:3]23[O:28][CH2:27][CH2:26][O:25][C:20]2([O:29][CH2:30][CH2:1][O:2]3)[CH2:21][CH2:22][CH2:23][CH3:24])[CH2:7][CH2:8][CH2:9]1

Participants

3

Reactant 2

HCID 9550DiazomethaneHCID 86737064HCID 86737064, compound

Product 1

HCID 86737062HCID 86737062, compound

Procedure

Into 0.2 g of 9,9;15,15-bis-(ethylenedioxy)-13-prostenoic acid, ethereal diazomethane solution is dropped until a pale yellow color just remains. The organic solution is washed several times with aqueous sodium acetate solution. The organic phase is dried over MgSO4 and the solvent distilled. As the residue, 9,9;15,15-bis-(ethylenedioxy)-13-prostenoic acid methyl ester is obtained.

Workup

  1. washThe organic solution is washed several times with aqueous sodium acetate solution
  2. dry with materialThe organic phase is dried over MgSO4
  3. distillationthe solvent distilled

Sources & evidence

ORD record
ord-ef29b758e2e24802af3b6354b1e28808
Source dataset
uspto-grants-1980_06
Patent number
US04209444

Reaction notes

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