Water → 1-(3,4-Methylenedioxyphenyl)-4-morpholino-1-butene-3-ol

HRID 1706867Notes

Reaction equation

HRID 1706867 reaction equation
[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([CH:10]=[CH:11][C:12](=[O:20])[CH2:13][N:14]3[CH2:19][CH2:18][O:17][CH2:16][CH2:15]3)=[CH:4][C:3]=2[O:2]1.O>CO>[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([CH:10]=[CH:11][CH:12]([OH:20])[CH2:13][N:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)=[CH:4][C:3]=2[O:2]1

Participants

4

Reactant 2

HCID 962WaterHCID 479671-(3,4-Methylenedioxyphenyl)-4-morpholino-1-butene-3-one

Product 1

HCID 479711-(3,4-Methylenedioxyphenyl)-4-morpholino-1-butene-3-ol

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

27.5 g of the ketone (0.1 M) obtained in Example 1 is dissolved in 300 cm3 of methanol and an aqueous solution of KBH4 is added dropwise. The reaction mixture is left overnight and decomposed with water. The product obtained is filtered and recrystallised in ethanol.

Workup

  1. additionan aqueous solution of KBH4 is added dropwise
  2. customThe product obtained
  3. filtrationis filtered
  4. customrecrystallised in ethanol

Sources & evidence

ORD record
ord-842c2a0ae5a34c11a258e3a737fab6a7
Source dataset
uspto-grants-1980_06
Patent number
US04209517

Reaction notes

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