Formaldehyde → HCID 3050515, compound

Participants

Reaction Steps

A mixture of 20 g of 1-(3,4-methylenedioxyphenyl)-1-pentene-3-one (0.1 mole), 3 g of paraformaldehyde (0.1 mole) and 12.2 g of morpholine hydrochloride (0.1 mole) in 100 cm3 of absolute alcohol adjusted to a pH of 3 is refluxed for 9 hours. The alcohol is removed and the product is taken up in water. The product is then extracted with chloroform, and the basic, aqueous phase is taken and re-extracted with benzene. A yellow oil is obtained which can be used for the reduction of Example 6.

Provenance & Evidence