Diisopropyl Ether → 2-[2-(2,4-Dichlorophenyl)ethyl]oxirane

HRID 1706891Notes

Reaction equation

HRID 1706891 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][CH2:10][CH:11]([CH2:13]Cl)[OH:12].[OH-].[Na+].O(C(C)C)C(C)C>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][CH2:10][CH:11]1[CH2:13][O:12]1

Participants

4

Reactant 3

HCID 7914Diisopropyl EtherHCID 14798Sodium HydroxideHCID 204768722,4-Dichloro-alpha-(chloromethyl)benzenepropanol

Product 1

HCID 198131652-[2-(2,4-Dichlorophenyl)ethyl]oxirane

Procedure

A solution of 87 parts of 2,4-dichloro-α-(chloromethyl)-benzenepropanol in 144 parts of concentrated sodium hydroxide solution and 350 parts of 2,2'-oxybispropane is stirred overnight at room temperature. The product is extracted with 2,2'-oxybispropane. The extract is washed with water, dried, filtered and evaporated. The oily residue is distilled, yielding [2-(2,4-dichlorophenyl)ethyl]oxirane; bp. 90°-98° C. at 0.01 mm. pressure.

Workup

  1. extractionThe product is extracted with 2,2'-oxybispropane
  2. washThe extract is washed with water
  3. customdried
  4. filtrationfiltered
  5. customevaporated
  6. distillationThe oily residue is distilled

Sources & evidence

ORD record
ord-510cc93acd7f4f7e861354b31da99b1b
Source dataset
uspto-grants-1980_06
Patent number
US04209447

Reaction notes

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