Potassium Cation → tert.-Butyl [6-(4-cyanophenyl)-5-(cyclobutylcarbonyl)-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-3,6-dihydropyrimidine-1(2H)-yl]acetate

HRID 170691Notes

Reaction equation

HRID 170691 reaction equation
[Br:39][CH2:40][C:41](=[O:42])[O:43][C:44]([CH3:45])([CH3:46])[CH3:47].[C:33](=[O:34])([O-:35])[O-:36].[CH3:48][N:49]([CH3:50])[CH:51]=[O:52].[CH:1]1([C:5](=[O:6])[C:7]2=[C:12]([CH3:13])[N:11]([c:14]3[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][cH:19]3)[C:10](=[O:24])[NH:9][CH:8]2[c:25]2[cH:26][cH:27][c:28]([C:29]#[N:30])[cH:31][cH:32]2)[CH2:2][CH2:3][CH2:4]1.[K+:37].[K+:38]>>[CH:1]1([C:5](=[O:6])[C:7]2=[C:12]([CH3:13])[N:11]([c:14]3[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][cH:19]3)[C:10](=[O:24])[N:9]([CH2:40][C:41](=[O:42])[O:43][C:44]([CH3:45])([CH3:46])[CH3:47])[CH:8]2[c:25]2[cH:26][cH:27][c:28]([C:29]#[N:30])[cH:31][cH:32]2)[CH2:2][CH2:3][CH2:4]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 79177tert-Butyl bromoacetateHCID 59684872HCID 59684872, compound

Product 1

HCID 59684827tert.-Butyl [6-(4-cyanophenyl)-5-(cyclobutylcarbonyl)-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-3,6-dihydropyrimidine-1(2H)-yl]acetate

Sources & evidence

ORD record
ord-fcb041b8c06a410cac20666c079f1e2a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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