Formaldehyde → HCID 20333077, compound
Reaction equation
[CH2:1]=O.[C:3]1([C:8]([NH:10][C:11](=[O:19])[NH:12][CH:13]2[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]2)=[O:9])[S:7][CH:6]=[CH:5][CH:4]=1.[NH:20]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:22]=[CH:21]1>>[NH:20]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[C:22]([CH2:1][N:16]2[CH2:17][CH2:18][CH:13]([NH:12][C:11]([NH:10][C:8](=[O:9])[C:3]3[S:7][CH:6]=[CH:5][CH:4]=3)=[O:19])[CH2:14][CH2:15]2)=[CH:21]1Participants
4
Procedure
Following the procedure of Example 1, formaldehyde, 4-(2-thenoyl)ureidopiperidine and indole are reacted together to obtain the title compound which is isolated as the hydrochloride mp 231°-232° C.
Workup
- customare reacted together
Sources & evidence
- ORD record
- ord-bb9559983fd740fd8dcaa9879887e71d
- Source dataset
- uspto-grants-1980_06
- Patent number
- US04209521
Reaction notes
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