Dimethylformamide → Glucose Monohydrate

HRID 1707030Notes

Reaction equation

HRID 1707030 reaction equation
C[C@@H]1[O:7][C@@H]([O:8][C@H:9]2[C@H:33]([O:34]C)[C@@:32]([OH:37])(C)[C:30](=[O:31])C3C=C4C(=O)C5C=C(OC)C=C(O)C=5C(=O)C4=[C:15]([OH:16])[C:10]2=3)[C@H](OC)[C@H](O)[C@H]1O.CN(C)C=[O:45]>C(Cl)(Cl)Cl.CO>[OH2:7].[O:31]=[CH:30][C@@H:32]([C@H:33]([C@@H:9]([C@@H:10]([CH2:15][OH:16])[OH:45])[OH:8])[OH:34])[OH:37]

Participants

4

Reactant 2

HCID 6228DimethylformamideHCID 70683013Steffimycin

Product 1

HCID 22814120Glucose Monohydrate

Reagents, catalysts & solvents 1

HCID 21584188Chloroform methanolSolvent

Procedure

Between about 36 and 48 hours of fermentation time, steffimycin is added to the fermentation as a dimethylformamide solution (25 mg/ml) to a final medium concentration of 25 mg/l. The fermentation is monitored using tlc on silica gel plates with CHCl3 :CH3OH (925:75) as the developing solvent system. The tlc procedure is conducted at half day intervals between the first half day and five days.

Workup

  1. custombetween the first half day and five days

Sources & evidence

ORD record
ord-50a7812046244584b40747121d835979
Source dataset
uspto-grants-1980_06
Patent number
US04209611

Reaction notes

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