HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Fluoroacetophenone → 3-(Dimethylamino)-1-(4-fluorophenyl)prop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Fluoroacetophenone | HCID 9828 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | 3-(Dimethylamino)-1-(4-fluorophenyl)prop-2-en-1-one | HCID 600539 | — |
Reaction Steps
A mixture of 5.0 g. of p-fluoroacetophenone and 10 ml. of dimethylformamide dimethylacetal is refluxed for 4 hours. Evaporation gives an oil which crystallizes with the addition of hexane to give the product, m.p. 83.5°-84° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04209621 |
| Source dataset | uspto-grants-1980_06 |
| ORD ID | ord-1df479f2c3e64a28b5806bf1484dfbe1 |
| Source note | uspto-grants-1980_06 |