3-(Dimethylamino)-1-phenyl-2-propen-1-one → HCID 178527861, compound

HRID 1707067Notes

Reaction equation

HRID 1707067 reaction equation
CN(C)[CH:3]=[CH:4][C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=O.[NH2:14][C:15]([NH2:17])=[S:16]>O>[SH:16][C:15]1[N:17]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH:4]=[CH:3][N:14]=1

Participants

4

Reactant 2

HCID 3534603-(Dimethylamino)-1-phenyl-2-propen-1-oneHCID 2723790Thiourea

Product 1

HCID 178527861HCID 178527861, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 17.5 g. of 3-dimethylaminoacrylophenone and 30.44 g. of thiourea is intimately mixed and fused at 180°-190° C. for one hour. The mixture is cooled and water is added and the desired compound is recovered by filtration, m.p. 203°-205° C.

Workup

  1. additionA mixture of 17.5 g
  2. temperatureThe mixture is cooled
  3. filtrationthe desired compound is recovered by filtration, m.p. 203°-205° C.

Sources & evidence

ORD record
ord-b24124d418164577b413617eda53f90f
Source dataset
uspto-grants-1980_06
Patent number
US04209621

Reaction notes

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