反应详情

In the manner described in Example 6, a solution of 48.6 g. of sodium methoxide and 42.0 g. of cyanoacetamide in 1000 ml. of methanol and 93.6 g. of 2-(2-chlorophenyl)-3-(dimethylamino)-2-propenal is refluxed for 16 hours to yield 30.0 g. of a tan solid. The solid is recrystallized from ethanol to yield the product of the Example as white needles, m.p. 252°-254° C.

1. customto yield 30.0 g
2. customThe solid is recrystallized from ethanol
3. customto yield the product of the Example as white needles, m.p. 252°-254° C.