Methanol → HCID 131718682, compound

HRID 1707214Notes

Reaction equation

HRID 1707214 reaction equation
[C:1]([OH:11])(=[O:10])[C@H:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[OH:3].[CH2:12]([NH2:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.CO>C(O)C>[C:1]([O-:11])(=[O:10])[C@H:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[OH:3].[CH2:12]([NH3+:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 7504BenzylamineHCID 439616(S)-mandelic acid

Product 1

HCID 131718682HCID 131718682, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

(S)-Mandelic acid (3.0 g; 22 mmol) was dissolved in ethanol (10 cm3) and added to a mixture of benzylamine (2.2 g; 20 mmol) and methanol (5 cm3). The white product was collected by filtration, recrystallized from water and dried in vacuo. Found: C, 69.2%; H, 6.6%; N, 5.4%. Calculated for C14H17NO3 : C, 69.47%; H, 6.62%; N, 5.40%. M.pt. 174°-175° C.

Workup

  1. filtrationThe white product was collected by filtration
  2. customrecrystallized from water
  3. customdried in vacuo

Sources & evidence

ORD record
ord-e92096112fc4497e876423fc26f9f709
Source dataset
uspto-grants-1994_10
Patent number
US05352388

Reaction notes

Loading…