4-Hydroxybenzoic Acid → HCID 178524489, compound

HRID 1707219Notes

Reaction equation

HRID 1707219 reaction equation
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:9][C:10]1[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[CH:12][CH:11]=1>CO>[OH:9][C:10]1[CH:18]=[CH:17][C:13]([C:14]([O-:16])=[O:15])=[CH:12][CH:11]=1.[CH2:1]([NH3+:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 1354-Hydroxybenzoic AcidHCID 7504Benzylamine

Product 1

HCID 178524489HCID 178524489, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Benzylamine (1.07 g; 10 mmol) was added dropwise to a solution of 4-hydroxybenzoic acid (1.38 g; 10 mmol) in methanol (10 cm3). A white solid formed immediately. The product was collected by filtration and recrystallized from water to produce white needle-like crystals. Found: C, 68.6%; H, 6.2%; N, 5.6%. Calculated for C14H15NO3 : C, 68.57%; H, 6.12%; N, 5.71%. M.pt. 229°-230° C.

Workup

  1. customA white solid formed immediately
  2. filtrationThe product was collected by filtration
  3. customrecrystallized from water
  4. customto produce white needle-like crystals

Sources & evidence

ORD record
ord-84c91295f0fc48328290042274a34a71
Source dataset
uspto-grants-1994_10
Patent number
US05352388

Reaction notes

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