反应详情

2.3 g (5 mmol) of the compound from Example IV are stirred for 5 h at 25° C. in 5 ml of dichloromethane and 5 ml of trifluoroacetic acid. After concentration, the crude product is chromatographed on silica gel 60 using dichloromethane/methanol (100:5). Yield: 1.8 g (87.6% of theory) Solidification point: 95°-98° C.

1. concentrationAfter concentration
2. customthe crude product is chromatographed on silica gel 60 using dichloromethane/methanol (100:5)
3. custom95°-98° C.